Introduction

GHK-Cu (glycyl-L-histidyl-L-lysine:copper), often called the “copper peptide,” is a naturally occurring compound found in human plasma, saliva, and urine. First identified in the 1970s, GHK-Cu is now widely studied for its potential role in skin repair, hair growth, wound healing, and tissue regeneration. In research and cosmetic contexts, it’s known as GHK-Cu peptide, GHK copper peptide, or simply copper peptide .

GHK-Cu Fast Facts

• Peptide sequence: Gly-His-Lys (GHK), forms a complex with copper ions (Cu²⁺)
  
• Where found: Human plasma, skin, saliva, urine
  
• Nicknames: GHK-Cu, GHK Cu Peptide, Copper Peptide, GHK Peptide, GHK Copper Peptide
  
• Primary functions in research: Promoting skin and tissue repair, supporting hair growth, modulating inflammation, and protecting against oxidative damage.
  
  

Why is GHK-Cu Called the “Copper Peptide”?

GHK is a naturally occurring tripeptide (three amino acids). When it binds to a copper ion, it becomes GHK-Cu—a biologically active copper peptide. This copper binding is believed to be central to GHK-Cu’s effects on tissue remodeling, antioxidant defense, and cellular signaling.

GHK-Cu in Research: Key Applications

• Skin regeneration: Supports collagen production, reduces wrinkles, and improves skin elasticity
  
• Hair growth: Promotes hair follicle stem cell activity and may increase hair density
  
• Wound healing: Accelerates tissue repair and reduces inflammation in animal and cell studies
  
• Anti-aging: May improve skin tone, reduce fine lines, and support youthful tissue structure
  
• Other effects: Investigated for nerve repair, organ protection, and anti-oxidant effects

How is GHK-Cu Used in Research and Cosmetics?

• Topical products: Skin creams, serums, and hair treatments (cosmetic use)
  
• Laboratory research: Cell culture and animal studies on wound healing, skin regeneration, and anti-aging
  
• Note: All research peptides—including GHK-Cu—sold for lab use are not for human consumption, diagnosis, or therapy outside approved clinical studies.

GHK-Cu vs. Other Peptides

• BPC-157 and TB-500: Focus more on muscle/tendon healing and systemic repair
  
• GHK-Cu: Especially valued for skin, hair, and cosmetic/dermatology applications, but also explored for broader regenerative effects
  
• Copper peptide: The umbrella term, but GHK-Cu is by far the best-studied copper-binding peptide in both research and cosmetic settings

Common Synonyms & Search Terms

• ghk-cu, ghk cu peptide, ghk-cu peptide, ghk copper peptide, copper peptide ghk-cu, ghk-cu copper peptide, ghk peptide, copper peptide, ghk/cu